Chromosome 16 (human) Totally Explained

Everything about Chromosome 16 Human totally explained

Chromosome 16 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 16 spans about 90 million base pairs (the building material of DNA) and represents just under 3 % of the total DNA in cells.
Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 16 probably contains between 850 and 1,200 genes.

Genes

The following are some of the genes located on chromosome 16:

ABCC6: ATP-binding cassette, sub-family C (CFTR/MRP), member 6
CCL17: Chemokine (C-C motif) ligand 17 (scya17)
CCL22: Chemokine (C-C motif) ligand 22 (scya22)
CX3CL1: chemokine (C-X3-C motif) ligand 1 (scyd1)
CREBBP: CREB binding protein (Rubinstein-Taybi syndrome)
COQ7: ubiquitin biosynthesis
GAN: giant axonal neuropathy (gigaxonin)
LITAF: lipopolysaccharide-induced TNF factor
MEFV: Mediterranean fever
PKD1: polycystic kidney disease 1 (autosomal dominant)
TAT: tyrosine aminotransferase
TSC2: tuberous sclerosis 2
CARD15 : NOD2/NOD-like receptor C2 (NLRC2)

Diseases & disorders

The following diseases are some of those related to genes on chromosome 16:

Autism

Charcot-Marie-Tooth disease

Charcot-Marie-Tooth disease, type 1

familial Mediterranean fever

giant axonal neuropathy

polycystic kidney disease

pseudoxanthoma elasticum

Rubinstein-Taybi syndrome

tuberous sclerosis

tyrosinemia

Inflammatory bowel disease

Crohn's DiseaseFurther Information

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